Task Area 5 applies the solutions developed in NFDI4Health directly in scientific practice. The use cases address central and current questions in health research – from prevention to care.

This allows the NFDI4Health FAIR-Services to be tested and transitioned into use. In the use case "Precision Prevention," we utilise our established network of epidemiological data holders and standardise complex biomarker data, which particularly reflect the transition from health to disease onset, to make them available for more precise prevention approaches. In the use case "Unlocking Mega-Cohorts for Joint Analysis of Rare Diseases," we work closely with the Marfan Centre at the German Heart Centre of the Charité. In this case, we expand existing international standards for cohort data to include rare diseases, enhance the interoperability of various data sources, and drive the internationalisation of NFDI4Health. In the use case "Common Data Model for German Health Data," from 2027 onwards, we will focus on health data from statutory health insurers and explore data models to improve data usage. Overall, in TA5, we actively engage user communities and other health data initiatives, support the FAIRification of large German data sources, and simultaneously prepare Germany's connection to the European Health Data Space.